Alcohol and opioids The concomitant use of alcohol and opioids raises the danger of sedation, respiratory depression, coma and death as a result of additive CNS depressant result. Concomitant use with alcohol just isn't advisable (see area 4.four).
In serious circumstances this will likely involve symptoms of circulatory and respiratory depression which may be lifestyle-threatening and very hardly ever lethal. Estimates of prevalence of extremely-fast metabolisers in several populations are summarized below:
Some recreational drugs, such as cannabis, also raise typical codeine side effects for instance sleepiness and dizziness.
Other people usually tend to get really serious Unwanted effects since a very substantial quantity of morphine is generated. Should you notice any of the next Unwanted effects, it's essential to prevent taking this medication and search for instant health care assistance: slow or shallow respiratory, confusion, sleepiness, tiny pupils, sensation or remaining Unwell, constipation, not enough hunger.
It's frequent for 2 tablets to become taken at a time. This equals a dose of 1000mg (1 gram) of paracetamol, which is the most suggested quantity of paracetamol per dose. You have to consequently not consider every other paracetamol containing remedies even though getting co-codamol.
You can get bacterial infections or bruise far more simply than common. This could be due to a blood problem (including agranulocytosis, neutropenia or thrombocytopenia)
When you have acquired co-codamol from the pharmacy you should not take it for much more than 3 times in a very row. Should you be nonetheless in pain after this time check with your medical professional or perhaps a pharmacist for advice.
Even so if your medical professional does prescribe co-codamol together with sedative medicines the dose and duration of concomitant cure really should be limited by your medical doctor.
Will not consider co-codamol when you are breastfeeding as codeine passes into breast milk and will influence your baby.
Should you be pregnant or breastfeeding, Assume you might be Expecting or are planning to Have got a little one, you have to talk to your medical professional or Chemist4U pharmacist for guidance in advance of using any new drugs.
Maintain this medication out of your sight and attain of kids. Do not use this medicine following the expiry day revealed around the pack. The expiry date refers back to the past day of that month.
Will not choose co-codamol if you are Expecting or Imagine there's a chance you're Expecting Until you may have reviewed this with your prescriber and the many benefits of procedure are considered to outweigh the potential hurt to the child.
These Co-codamol tablets are for oral administration and will be taken with more info or without food stuff. Please see the patient info leaflet To find out more.
monoamine oxidase inhibitors (MAOIs) for instance moclobemide and phenelzine Employed in the therapy of depression